Author

Tosca Dalessi

University of ZurichORCID 0009-0008-1845-8227Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Hassan FazilatyiD· 3 shared Tomáš ValentaiD· 3 shared Ab MeijsiD· 2 shared Isabelle Catherine ArnoldiD· 2 shared Michael David BrüggeriD· 2 shared Michael M. ScharliD· 2 shared Randall J. PlattiD· 2 shared Simon Lampart· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersCancer Biology

Hassan FazilatyORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 25, 2026

Acquired epithelial Wnt7b secretion establishes autocrine WNT dependency in BRAF mutant colorectal cancer

Simon Lampart, Tasnim Khadam-Al-Jame, Peter Leary…·Tomáš Valenta

This study identifies Wnt7b as a critical autocrine WNT ligand required for survival of BRAF-mutant colorectal cancer organoids and shows its association with poor patient survival in human tumors.

DOI 10.64898/2026.09.24.754033

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintDec 13, 2024

Eosinophils restrict CRC metastasis by inhibiting pro-tumorigenic SPP1+ macrophage differentiation

Kristina Handler, Deeksha Raju, Alessandra Gurtner…·Isabelle Catherine Arnold

This study shows eosinophils inhibit CRC metastasis by blocking SPP1+ macrophage differentiation, using transcriptomics and a murine model.

5 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 8, 2024

An oncoembryology approach uncovers SoxC-driven regulation of colon development and cancer

Tosca Dalessi, Tomáš Valenta, Giulia Moro…·Hassan Fazilaty

This study introduces oncoembryology to identify SoxC transcription factors as regulators of colon development and cancer, showing their role in tumor growth and metastasis.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky