Author

Zeeba Manavi

Georgetown UniversityORCID 0000-0001-8704-6164Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

George S. MelchoriD· 2 shared Jeffrey K. HuangiD· 2 shared Dorothy P. SchaferiD· 1 shared Enrique ÁlvareziD· 1 shared Jason R. PlemeliD· 1 shared Jingwen HuiD· 1 shared Lana T. HoiD· 1 shared Maryna BaydyukiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

George S. MelchorORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedMar 7, 2025

Senescent-like microglia limit remyelination through the senescence associated secretory phenotype

Phillip S. Gross, Violeta Durán‐Laforet, Lana T. Ho…·Jeffrey K. Huang

This study shows that senescent microglia impair remyelination in young mice but not aged mice, with CCL11 in SASP inhibiting oligodendrocyte maturation.

66 citationstop 1%

mousestatistical model

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 25, 2024

Dissecting the evolving cellular landscape of a remyelinating microenvironment

George S. Melchor, Maryna Baydyuk, Zeeba Manavi…·Jeffrey K. Huang

The paper analyzes gene expression dynamics in a remyelinating microenvironment using single nucleus RNA sequencing in mice, revealing shifts in microglial, astrocytic, and fibroblast activities linked to oligodendrocyte differentiation.

3 citations

mousescRNA-seq

𝕏 PostBluesky