Violeta Durán‐Laforet

Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling

This study shows microglia instruct astrocyte-synapse interactions via Wnt signaling, enabling microglia to remove synapses during activity-dependent remodeling.

Senescent-like microglia limit remyelination through the senescence associated secretory phenotype

This study shows that senescent microglia impair remyelination in young mice but not aged mice, with CCL11 in SASP inhibiting oligodendrocyte maturation.

An orbitocortical-thalamic circuit suppresses binge alcohol-drinking.

The paper identifies a GABAergic neuronal ensemble in the medial orbitofrontal cortex that suppresses binge alcohol drinking by projecting to the mediodorsal thalamus.

Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis

The paper investigates how Th17 cytokines influence microglial and blood-brain barrier responses during post-infectious encephalitis using single-cell RNA sequencing and spatial transcriptomics.

A newly-recognized population of residual neural crest cells in the adult leptomeninges is re-activated for vascular repair

The paper identifies residual neural crest stem cells in adult mouse meninges that are reactivated for vascular repair after injury.