Sarah E. McGovern

The paper shows that chromatin states, not just circadian transcription factors, coordinate diurnal gene expression in Drosophila photoreceptor neurons by aligning gene phases with promoter, enhancer, or repressive chromatin signatures.

This study shows that aging in Drosophila retina causes broad epigenetic shifts, including decreased histone methylation, which disrupt gene expression rhythms despite a functional circadian clock.

The paper investigates how active histone methylation marks, specifically H3K4me3 and H3K36me3, change with age in Drosophila photoreceptors and their impact on splicing and visual function.

The paper shows that Dnmt3bas coordinates transcriptional induction and alternative splicing of Dnmt3b to produce catalytically active Dnmt3b1.