Author

Tomáš Mašek

Charles UniversityORCID 0000-0001-8732-0565Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

Martin PospíšekiD· 3 shared Michal SýkoraiD· 2 shared Václav VopálenskýiD· 2 shared Adéla PřibylováiD· 1 shared Alexander W. BruceiD· 1 shared Andrea HauserováiD· 1 shared Andrea ZounkováiD· 1 shared Andrej ŠušoriD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersMolecular Biology

Martin PospíšekORCID

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4 papers

Recent·Most cited

Plant BiologybioRxivPreprintJul 22, 2026

CRISPR-Cas9 Induced Knockout of BEL5 in Tetraploid Potato: Optimized Methodology via Repeated de novo Regeneration and Impact on Tuberization

Andrea Zounková, Daniele Chirivì, Adéla Přibylová…·Petra Mašková

This study knocks out the BEL5 gene in tetraploid potato using CRISPR-Cas9, showing delayed tuberization but comparable yields, and develops improved gene editing methodology for polyploid crops.

DOI 10.64898/2026.07.21.739726

plant (other)whole-genome sequencing

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Molecular BiologyNature CommunicationsPeer-reviewedDec 22, 2025

Transcripts of vaccinia virus postreplicative genes do not contain a 5' methylguanosine cap

Václav Vopálenský, Michal Sýkora, Zora Mělková…·Martin Pospíšek

The paper shows that vaccinia virus postreplicative mRNAs lack a 5' methylguanosine cap and have nontemplated poly(A) leaders, controlled by promoter sequences.

2 citations

experimental assay

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Developmental BiologybioRxivNov 30, 2020

p38-MAPK mediated rRNA processing and translation regulation enables PrE differentiation during mouse blastocyst maturation.

Martin Pospíšek, Alexander W. Bruce, Pablo Bora…·Anna Ajduk

This study shows that p38-MAPK regulates PrE differentiation during mouse blastocyst maturation by controlling translation and rRNA processing through Mybpp1a.

2 citations

mouseproteomics

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Molecular BiologyFrontiers in MicrobiologyPeer-reviewedOct 30, 2019

Messenger RNAs transcribed from yeast linear cytoplasmic plasmids possess unconventional 5’ and 3’ UTRs and suggest a novel mechanism of translation

Václav Vopálenský, Michal Sýkora, Tomáš Mašek, Martin Pospíšek

11 citations

yeastmetagenomics

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