The paper shows that vaccinia virus postreplicative mRNAs lack a 5' methylguanosine cap and have nontemplated poly(A) leaders, controlled by promoter sequences.

Nature Communications · Dec 22, 2025Peer-reviewedMolecular Biology

p38-MAPK mediated rRNA processing and translation regulation enables PrE differentiation during mouse blastocyst maturation.

Martin Pospíšek, Alexander W. Bruce, Pablo Bora, Tomáš Mašek, Lenka Gahurová, David Potěšil, Andrea Hauserová, Denisa Jansová, Zbyněk Zdráhal, Andrej Šušor, Anna Ajduk

This study shows that p38-MAPK regulates PrE differentiation during mouse blastocyst maturation by controlling translation and rRNA processing through Mybpp1a.

bioRxiv · Nov 30, 2020Developmental Biology

Messenger RNAs transcribed from yeast linear cytoplasmic plasmids possess unconventional 5’ and 3’ UTRs and suggest a novel mechanism of translation

Václav Vopálenský, Michal Sýkora, Tomáš Mašek, Martin Pospíšek

Frontiers in Microbiology · Oct 30, 2019Peer-reviewedMolecular Biology

Transcription apparatus of the yeast killer DNA plasmids: Architecture, function, and evolutionary origin

Michal Sýkora, Martin Pospíšek, Josef Novák, Silvia Mrvová, Libor Krásný, Václav Vopálenský

The paper describes the architecture, function, and evolutionary origin of the transcription machinery of yeast killer DNA plasmids, showing similarities to poxviral systems.

PLoS Pathogens · Oct 22, 2018Peer-reviewedMolecular Biology