Robson A.S. Santos

This study evaluates the effects of rilmenidine on cardiac function and inflammation in a mouse model of insular hemorrhagic stroke, finding it prevents major cardiac changes.

This study investigates how diseased extracellular matrix (ECM) from MASH-derived organs affects cell physiology and disease progression in vitro and in vivo.

This study identifies and characterizes alamandine-(1-5), a new RAS component with unique biological activities and increased plasma concentration in nephropathic patients.

This study identifies MrgD's role in modulating neurotransmission in the nigrostriatal pathway through proteomic analyses and behavioral assays, revealing impaired synaptic exocytosis and altered behavior in MrgD-deficient mice.

This study identifies angiotensin-(1-5) as a potent endogenous agonist of the AT2-receptor, showing its ability to increase nitric oxide release and lower blood pressure through AT2R-mediated mechanisms.

This study identifies MAO-B hyperactivation as a key contributor to cardiac dysfunction in MrgD-KO mice, showing that MAO-B inhibition reverses contractile defects.