Author

Irina Golovleva

Umeå UniversityORCID 0000-0001-8741-0616Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Albert W. ChengiD· 1 shared Daniel Urrutia-CabreraiD· 1 shared Fei‐Ting HsuiD· 1 shared Fred Kuanfu CheniD· 1 shared Guei‐Sheung LiuiD· 1 shared Ida Maria WestiniD· 1 shared Keith R G MartiniD· 1 shared Raymond C.B. WongiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Albert W. ChengORCID

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1 paper

Recent·Most cited

Using RNA-targeting CRISPR-Cas13 and engineered U1 systems to reduce ABCA4 splice variants in Stargardt disease

Roxanne Hsiang-Chi Liou, Daniel Urrutia-Cabrera, Ida Maria Westin, Irina Golovleva, Guei‐Sheung Liu, Satheesh Kumar, Samuel McLenachan, Fred Kuanfu Chen, Fei‐Ting Hsu, Tom Edwards, Keith R G Martin, Albert W. Cheng, Raymond C.B. Wong

This study evaluates RNA-targeting CRISPR-Cas13 and engineered U1 systems to reduce mis-spliced ABCA4 variants in Stargardt disease, showing significant reductions in disease-causing splice variants.

bioRxiv · Mar 8, 2024 · PreprintMolecular Biology