Jolien J. E. van Hooff

This study identifies 908 new isomorphic eukaryotic signature proteins in Asgard archaea, suggesting their ancestor was more complex than previously thought.

This study reconstructs the evolution of SMC complexes across eukaryotes, showing LECA had all four types and condensin II was repeatedly lost.

This study identifies KKT14-KKT15 in kinetoplastids as divergent orthologs of Bub1/BubR1-Bub3, suggesting a unique mechanism for chromosome segregation fidelity in trypanosomes.

The paper identifies biallelic mutations in CENATAC as a cause of constitutional aneuploidy by disrupting minor intron splicing and causing chromosome segregation errors.