Author
University of ChicagoORCID 0000-0001-8760-0700Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Darren A. Sherrell, Alex Lavens, Mateusz Wilamowski…·A. Joachimiak
The paper describes a new system for serial crystallography data collection using a 3D printed mesh-holder and high-performance computing pipeline, applied to two beta-lactamases.
Mateusz Wilamowski, Darren A. Sherrell, G. Minasov…·A. Joachimiak
The paper determines the crystal structures of SARS-CoV-2 Nsp10/16 complexes before and after methylation, revealing the mechanism of RNA capping and its role in viral evasion of host defenses.
Youngchang Kim, Jacek Wower, N. Maltseva…·A. Joachimiak
The paper shows that Tipiracil inhibits SARS-CoV-2 Nsp15 by binding to its uridine site, supporting its potential as a drug scaffold for antiviral development.
Youngchang Kim, Robert P. Jedrzejczak, N. Maltseva…·A. Joachimiak
The paper reports the high-resolution crystal structure of SARS-CoV-2 Nsp15/NendoU and compares it with structures from SARS and MERS coronaviruses.