Pascale Zimmermann

This paper introduces a genetic method to modify sEV surfaces with nanobodies, showing enhanced uptake by target cells.

The paper shows ADAM10 regulates sEV composition and signaling by cleaving receptors and sorting proteins, shifting sEVs from content delivery to contact-dependent signaling.

This study measures the capture, internalization, and cytosolic delivery of extracellular vesicle-embedded syntenin, showing high delivery efficiency but low internalization rates.

This study shows syntenin facilitates ECM degradation by controlling MT1-MMP secretion in sEV and invadopodia formation in TNBC cells.

The paper describes the development of PDZome 2.0, a Yeast Two-Hybrid resource for PDZ domain interactions, showing improved performance over the previous version using HPV16 E6 as a bait.