Author

Peter Jay Hotez

Baylor UniversityORCID 0000-0001-8770-1042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:genome assembly· 1 Organism:mouse· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

María Elena BottazziiD· 3 shared Bin ZhaniD· 2 shared Brian P. KeeganiD· 2 shared Cristina PovedaiD· 2 shared Jason T. KimataiD· 2 shared Jeroen B. K. PolletiD· 2 shared Junfei WeiiD· 2 shared Jungsoon LeeiD· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

María Elena BottazziORCID

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3 papers

Recent·Most cited

Molecular BiologyVaccinePeer-reviewedMay 8, 2022

Receptor-binding domain recombinant protein on alum-CpG induces broad protection against SARS-CoV-2 variants of concern

Jeroen B. K. Pollet, Ulrich Strych, Wen‐Hsiang Chen…·María Elena Bottazzi

This study evaluates a SARS-CoV-2 RBD subunit vaccine in mice, showing that adding CpG enhances immune response and neutralizing antibodies against multiple variants.

42 citationstop 3%

mouseexperimental assay

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Molecular BiologyProtein Expression and PurificationPeer-reviewedOct 21, 2021

Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain, RBD203-N1 as a COVID-19 Protein Vaccine Candidate

Wen‐Hsiang Chen, Jeroen B. K. Pollet, Ulrich Strych…·María Elena Bottazzi

This paper describes the development of a recombinant SARS-CoV-2 RBD vaccine candidate produced in yeast, showing high purity, stability, and immunogenicity in mice.

49 citations

yeastprotein structure

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GenomicsFrontiers in Cellular and Infection MicrobiologyPeer-reviewedMar 3, 2021

Repeat-driven generation of antigenic diversity in a major human pathogen, Trypanosoma cruzi

Carlos N. Talavera-López, Louisa Alexandra Messenger, Michael D. Lewis…·Björn Andersson

The paper presents an improved genome assembly of Trypanosoma cruzi and reveals a unique genomic structure involving subtelomeric regions and retrotransposons contributing to antigenic variation.

56 citationstop 3%

whole-genome sequencingstatistical model

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