Yanqing Sun

The paper presents 320 nearly-complete East Asian genome assemblies, revealing new genetic diversity and structural variations not present in existing global pangenomes.

Over 8,000 gapless human centromeres reveal population-stratified satellite-array, inversion and haplotype variation, multiple candidate kinetochore sites in 16.8% of centromeres, and single-base substitution rates comparable to flanking pericentromeres.

The paper introduces ASMaid, a method to detect archaic introgression sequences in human genomes, revealing more complete and diverse archaic segments than previous methods.

This study analyzes rice centromeres to understand their genetic diversity and evolution, finding that structural variations and retrotransposon insertions drive centromere innovation.