Dongya Wu

The paper examines copy-number variation in the human pepsinogen A gene across Eurasia, linking it to dietary adaptation and selective pressures.

PanSVmerger reduces redundant multiallelic structural variants in pangenome graphs with minimal loss of sensitivity, improving precision and F1-score.

The paper presents 320 nearly-complete East Asian genome assemblies, revealing new genetic diversity and structural variations not present in existing global pangenomes.

The paper introduces ASMaid, a method to detect archaic introgression sequences in human genomes, revealing more complete and diverse archaic segments than previous methods.

The paper develops a method to detect and analyze NUMTs in human and non-human primate genomes, revealing their genomic features, population dynamics, and evolutionary implications.

The paper identifies novel structural variants and archaic introgressions in Tibetan genomes linked to high-altitude adaptation.

The paper presents haplotype-resolved T2T assemblies of two MZ twins, revealing genomic and epigenetic divergence, including structural variation and DNA methylation differences.

This study analyzes rice centromeres to understand their genetic diversity and evolution, finding that structural variations and retrotransposon insertions drive centromere innovation.

This study presents genome assemblies and analyses of macaques to explore genetic variation, population history, and evolutionary differences between species and humans.

GFFx provides a fast, scalable toolkit for genome annotation access, improving runtime and scalability over existing tools.

GCI evaluates genome assembly continuity at single nucleotide resolution to determine how close an assembly is to T2T standards.

This study analyzes genome evolution in Asian rapeseed, showing divergence from European rapeseed, introgression events, and their impacts on genetic diversity and deleterious variations.