Dynamic phosphoproteomics and proteomics uncover Leishmania donovani-driven ferritin hijacking, contributing to the control of iron homeostasis and iron-related oxidative stress
Sharvani Shrinivas Shintre, Florent Dingli, Nicolai Meyerhöfer, Olivier Gorgette, Catherine Thouvenot, David B. Blumenthal, Damarys Loew, Anne Nerissa A. Silvestre, Najma Rachidi
This study identifies how Leishmania donovani hijacks host ferritin to create an iron reservoir, protecting against oxidative stress and ferroptosis.
bioRxiv · Feb 25, 2026 · PreprintMicrobiology