Cancer BiologybioRxivPreprint
CISH, a novel intracellular immune checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints
Florencia Cano, Alberto Bravo‐Blas, Mathilde Colombé…·Tom Henley
This study shows that deleting CISH enhances T cell anti-cancer functions more than other intracellular checkpoints, improving tumor antigen recognition and killing in CAR-T cells.