Author

Florencia Cano

Intima Bioscience (United States)ORCID 0000-0003-0695-7551Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adrian HaydayiD· 1 shared Alberto Bravo‐BlasiD· 1 shared Beau R. WebberiD· 1 shared Branden S. MoriarityiD· 1 shared Chiara Cerrato· 1 shared Christopher Austin KlebanoffiD· 1 shared Ellie Burns· 1 shared Emil LouiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Adrian HaydayORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 16, 2026

Atypical T cell receptor signalling permits distinct gut gd T cell responses to healthy versus dysregulated tissues

Leticia Monin, Florencia Cano, James Axford…·Adrian Hayday

The paper identifies an atypical TCR signaling pathway in gut γδ T cells that limits activation in healthy tissues but allows full responses during tissue perturbation.

DOI 10.64898/2026.10.09.757810

mouseproteomics

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Cancer BiologybioRxivPreprintApr 26, 2025

CISH, a novel intracellular immune checkpoint, in comparison and combination to existing and emerging cancer immune checkpoints

Florencia Cano, Alberto Bravo‐Blas, Mathilde Colombé…·Tom Henley

This study shows that deleting CISH enhances T cell anti-cancer functions more than other intracellular checkpoints, improving tumor antigen recognition and killing in CAR-T cells.

1 citation

humangenetic perturbation / CRISPR

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