Katelyn X. Li

This paper integrates 36 single-cell transcriptomics datasets from human neural organoids into a unified atlas to assess cell type coverage and compare organoid protocols with primary brain tissue.

The paper investigates how astrocyte regional specialization develops in mouse and marmoset brains using single-nucleus RNA sequencing and expansion microscopy, finding significant regional and developmental changes in gene expression and morphology.

This study shows that SKA2-regulated hyperactive secretory autophagy contributes to neuroinflammation and neurodegeneration in Alzheimer's disease.

The paper analyzes single-nucleus RNA sequencing data from marmoset brain cells to show that neuronal identity is more influenced by developmental origin than functional class.