Joy Otten

This study uses spatial transcriptomics to show gene expression changes across brain regions in mice after auditory threat conditioning, revealing altered transcriptional connectivity involving steroidogenic factor 1.

This study shows that SKA2-regulated hyperactive secretory autophagy contributes to neuroinflammation and neurodegeneration in Alzheimer's disease.

This study identifies Ptgs2 as a stress-induced gene in specific prefrontal cortical neurons that mediates anxiety-like behaviors in mice.

This study identifies similar transcriptional responses to acute and chronic alcohol drinking in mouse amygdala subnuclei, highlighting shared pathways and potential therapeutic targets for AUD.