Margaret E. Schroeder

RnR-ExM: Robust Non-rigid Registration Challenge for Expansion Microscopy Volumes

The paper presents a challenge for 3D registration of expansion microscopy volumes, evaluates top methods, and highlights future directions for ExM registration.

Expansion Revealing of Pathology Resolves Nanostructures Associated with Inflammatory Phenotypes in COVID-19 Decedent Human Brain Tissue

The paper introduces ExRPath and 15ExMPath techniques to expand human brain tissue for nanostructure analysis, revealing amyloid nanoclusters associated with SARS-CoV-2 in COVID-19 patients.

Astrocyte regional specialization is shaped by postnatal development

The paper investigates how astrocyte regional specialization develops in mouse and marmoset brains using single-nucleus RNA sequencing and expansion microscopy, finding significant regional and developmental changes in gene expression and morphology.

A marmoset brain cell census reveals influence of developmental origin and functional class on neuronal identity

The paper analyzes single-nucleus RNA sequencing data from marmoset brain cells to show that neuronal identity is more influenced by developmental origin than functional class.

A multilayer network model of neuron-astrocyte populations in vitro reveals mGluR5 inhibition is protective following traumatic injury

The paper uses a multilayer network model to study neuron-astrocyte interactions in vitro, finding that mGluR5 inhibition protects against traumatic injury effects on neuronal networks.