Author

Karina S. Vitanova

University College LondonORCID 0000-0001-8800-4150Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Frances A. EdwardsiD· 2 shared Jack I. WoodiD· 2 shared Jörg HanriederiD· 2 shared Alison VanSchoiackiD· 1 shared Anders MeibomiD· 1 shared Aya Balbaa· 1 shared Carsten HopfiD· 1 shared Damian M. CummingsiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Frances A. EdwardsORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 26, 2022

Upregulation of Trem2 expression occurs exclusively on microglial contact with plaques

Jack I. Wood, Eugenia Wong, Ridwaan Joghee…·Frances A. Edwards

The paper shows that Trem2 gene expression in microglia is upregulated only when they contact plaques, and this effect is reduced by the Trem2R47H mutation.

DOI 10.1101/2022.01.26.477873

mousespatial transcriptomics

𝕏 PostBluesky

NeuroscienceScience AdvancesPeer-reviewedJun 16, 2021

Imaging stable isotope labelling kinetics (iSILK) for following spatial Aβ plaque aggregation dynamics in evolving Alzheimers disease pathology

Wojciech Michno, Katie M. Stringer, Thomas Enzlein…·Jörg Hanrieder

The paper uses iSILK to track Aβ plaque aggregation dynamics in AD mouse models, identifying cortical deposition and structural heterogeneity in plaque composition.

47 citationstop 2%

mouseimaging

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