Carla Cuní‐López

This study shows APOE genotypes alter astrocytic lipid droplet proteomes and dynamics, with APOE4 showing resistance to lipophagy, suggesting impaired clearance as a mechanism for AD risk.

This study shows APOE4 impairs endocytosis in astrocytes by altering membrane mechanics, and INPP5D restores this process by promoting clathrin curvature and maturation.

This study examines how wildfire smoke and diesel exhaust affect inflammatory responses in aging human microglia, showing distinct temporal and molecular effects on oxidative stress and cytokine profiles.

The paper uses olfactory cells from Alzheimer's patients to identify gene expression changes linked to cognitive decline.

This paper develops a method to generate monocyte-derived microglia from ALS patient blood, revealing functional impairments and pathological features associated with disease progression.

This study develops 3D models of Alzheimer's patient microglia that show distinct disease features and drug responses compared to 2D cultures.