NeurosciencebioRxivPreprint
Ketone body beta-hydroxybutyrate restores neuronal Tau proteostasis via ketolysis-independent mechanism
Leigh-Ana M. Rossitto, Jamie Foo, Julia M Di Silvestri…·Xu Chen
This study shows that beta-hydroxybutyrate (betaHB) improves neuronal Tau proteostasis and reduces Tau aggregation in tauopathy models, independent of its ketolysis for ATP production.
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