Author

Daniel Muñoz-Mayorga

University of California San DiegoORCID 0000-0002-4961-9256Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Suborno JatiiD· 3 shared Kechun Tang· 2 shared Anna Y Dai-Liu· 1 shared Chen XuiD· 1 shared Debashis SahooiD· 1 shared Dennis W. DicksoniD· 1 shared Gourisankar GhoshiD· 1 shared Irene LitvaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Suborno JatiORCID

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Author profile →

3 papers

Recent·Most cited

Ketone body beta-hydroxybutyrate restores neuronal Tau proteostasis via ketolysis-independent mechanism

Leigh-Ana M. Rossitto, Jamie Foo, Julia M Di Silvestri, Leanne M Lehmann, Melina Brunelli, Yuhang Nie, Daniel Muñoz-Mayorga, Qiang Xiao, Anna Y Dai-Liu, Suborno Jati, Meghan Rossi, Richard Daneman, Jeffery W. Kelly, John C. Newman, Samuel A. Myers, Xu Chen

This study shows that beta-hydroxybutyrate (betaHB) improves neuronal Tau proteostasis and reduces Tau aggregation in tauopathy models, independent of its ketolysis for ATP production.

bioRxiv · Feb 2, 2026 · PreprintNeuroscience

Catestatin ameliorates tauopathy and amyloidogenesis via adrenergic inhibition

Suborno Jati, Satadeepa Kal, Daniel Muñoz-Mayorga, Kechun Tang, Debashis Sahoo, Xu Chen, Sushil K. Mahata

This study shows that Catestatin reduces Tau pathology and amyloid plaque formation by inhibiting adrenergic signaling in mouse models of neurodegenerative diseases.

bioRxiv · Jan 4, 2026 · PreprintNeuroscience

Chromogranin A Deficiency Attenuates Tauopathy by Altering Epinephrine Alpha-Adrenergic Receptor Signaling

Suborno Jati, Daniel Muñoz-Mayorga, Shandy Shahabi, Kechun Tang, Yuren Tao, Dennis W. Dickson, Irene Litvan, Gourisankar Ghosh, Sushil Kumar Mahata, Chen Xu

This study shows that CgA deficiency reduces tau pathology and improves cognitive function in tauopathy models by modulating epinephrine-alpha-adrenergic receptor signaling.

bioRxiv · Jun 11, 2024 · PreprintNeuroscience