Andreas Schlösser

PRICE 2 improves detection of short and overlapping ORFs using group LASSO regularization, outperforming existing tools and enabling discovery of more cryptic MHC-I peptides.

This study models Fabry disease in human sensory neurons and finds axon guidance deficits and reduced neurite length due to Gb3 accumulation, with partial rescue by AGAL enzyme supplementation.

This study identifies m54.5 as a novel gene within the conserved MCMV DNA polymerase locus that encodes a protein regulating cell cycle arrest, with functional similarity to HCMV UL21a but not essential for viral replication.

This study investigates NONO protein-protein interactions in response to DNA damage and finds that etoposide treatment does not significantly alter these interactions.

This study uses SILAC-based quantification to analyze how MAPK inhibitors affect the immunopeptidome in melanoma cells, identifying potential targets for immunotherapy.

The paper analyzes the N-terminome of Physcomitrella to reveal N-terminal methylation of mitochondrial proteins and identifies a methyltransferase involved in plastid, mitochondrial, and cytosolic methylation.

The paper shows that pre-stimulating T cells with tumor-specific peptides can overcome immune checkpoint inhibitor resistance in hypermutated colorectal cancer cells.

The paper identifies Sparkly, a novel neuropeptide precursor gene regulated by Alk signaling in Drosophila CNS, through integration of TaDa and scRNA-seq data.

The paper introduces Sylites, fluorogenic probes for visualizing inhibitory synapses with high contrast and selectivity, enabling precise nanoscopic measurements and 3D distribution analysis in brain tissue.

The paper identifies TIM phosphorylation sites in Drosophila and shows that CK2-dependent phosphorylation of TIM(S1404) regulates nuclear export and circadian rhythms, with implications for human FASPS.

This study identifies dCPD as a critical enzyme for neuropeptide processing in Drosophila, showing its role in behavior and survival.