Author

Jaekwang Jeong

Yale UniversityORCID 0000-0001-8865-2545Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

John J. WysolmerskiiD· 3 shared Jungmin ChoiiD· 3 shared Jae Hun ShiniD· 2 shared Jaechul LimiD· 2 shared Kwangmin YooiD· 2 shared Alfred L.M. BothwelliD· 1 shared Hyun Seop Tae· 1 shared In‐Hyun ParkiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCancer Biology

John J. WysolmerskiORCID

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3 papers

Recent·Most cited

Cancer BiologyBreast Cancer ResearchPeer-reviewedMay 19, 2025

Erbin interacts with NHERF1 and Ezrin to stabilize a membrane ErbB2 signaling complex in HER2-positive breast cancer

Jaekwang Jeong, Kwangmin Yoo, Jong Won Lee…·John J. Wysolmerski

The paper shows Erbin interacts with NHERF1 and Ezrin to stabilize a membrane HER2 signaling complex in HER2-positive breast cancer, enhancing HER2 stability and transforming ability.

4 citations

humanmouse

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Cancer BiologybioRxivPreprintApr 16, 2024

A FOXA1/SPDEF Co-regulatory Axis Drives ERBB2 and Suppresses TEAD/YAP-Driven EMT to Maintain Luminal Identity in HER2+ Breast Cancer

Jaekwang Jeong, Jong Won Lee, Seungsoo Kim…·Jungmin Choi

This study identifies a FOXA1/SPDEF co-regulatory axis that drives ERBB2 expression and suppresses EMT in HER2+ breast cancer, maintaining luminal identity and serving as a therapeutic target.

1 citation

humanbulk RNA-seq

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Cancer BiologybioRxivApr 12, 2024

Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties

Jae Hun Shin, Jooyoung Park, Jaechul Lim…·Alfred L.M. Bothwell

This study shows DKK2 is required for colon cancer metastasis by generating cancer cells with Paneth cell properties through HNF4A regulation.

6 citations

mousebulk RNA-seq

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