ImmunologybioRxivPreprint
Uncovering an unconventional JAK1/2-STAT3 branch in macrophage IFNγ signaling
Mees Botman, Josje M.A. Huisman, Alexandra Drakaki…·Marten A. Hoeksema
The paper identifies an unconventional JAK1/2-STAT3 signaling pathway in macrophage IFNγ responses, showing STAT3 activation and heterodimerization with STAT1, but limited gene regulatory contribution.
DOI 10.1101/2025.08.13.667888