Molecular BiologyNature Structural & Molecular BiologyPeer-reviewed
Mechanism of receptor assembly via the pleiotropic adipokine Leptin
Alexandra Tsirigotaki, Ann Dansercoer, Koen H. G. Verschueren…·Kenneth Verstraete
This study reveals the structure and mechanism of Leptin-mediated LEP-R assembly, showing a 3:3 stoichiometry and highlighting the role of Leptin restructuring in activating signaling.
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