BiochemistrybioRxivPreprint
Catalytic pocket of Clr4 (Suv39h) methyltransfer-ase serves as a substrate receptor for Cullin 4-dependent histone H3 ubiquitination
Katarína Pšenáková, Swapnil S. Parhad, João A. Paulo…·Danesh Moazed
This study shows that the catalytic pocket of Clr4 (Suv39h) acts as a receptor for Cul4-dependent H3K14 ubiquitination, which regulates Clr4's methylation activity on H3K9.