Author

Swapnil S. Parhad

Howard Hughes Medical InstituteORCID 0000-0002-5723-9384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1

Frequent Co-Authors

Danesh MoazediD· 1 shared Emily F. Patterson· 1 shared Gen Zhang· 1 shared João A. PauloiD· 1 shared Katarína PšenákováiD· 1 shared Lucas FarnungiD· 1 shared Marcus Adrian CheekiD· 1 shared Marian KalocsayiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Danesh MoazedORCID

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2 papers

Recent·Most cited

Catalytic pocket of Clr4 (Suv39h) methyltransfer-ase serves as a substrate receptor for Cullin 4-dependent histone H3 ubiquitination

Katarína Pšenáková, Swapnil S. Parhad, João A. Paulo, Xinyue Liu, Emily F. Patterson, Rachel Watson, Marcus Adrian Cheek, Michael‐Christopher Keogh, Marian Kalocsay, Steven P. Gygi, Lucas Farnung, Danesh Moazed

This study shows that the catalytic pocket of Clr4 (Suv39h) acts as a receptor for Cul4-dependent H3K14 ubiquitination, which regulates Clr4's methylation activity on H3K9.

bioRxiv · Aug 28, 2025 · PreprintBiochemistry

Adaptive evolution targets a piRNA precursor transcription network

Swapnil S. Parhad, Tianxiong Yu, Gen Zhang, Nicholas P. Rice, Zhiping Weng, William E. Theurkauf

The paper identifies a network involving Cuff, TRF2, and CtBP that balances canonical and non-canonical piRNA precursor transcription in Drosophila.

Cell Reports · Feb 1, 2020Peer-reviewedGenetics