Author
VIB-KU Leuven Center for Brain & Disease ResearchORCID 0000-0001-8880-9311Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Mathias De Decker, Pavol Zelina, Thomas G. Moens…·Philip Van Damme
This study identifies C21orf2 mutations in ALS as causing cilia dysfunction and impaired sonic hedgehog signaling in motor neurons.
Chen Eitan, Aviad Siany, Elad Barkan…·Eran Hornstein
The paper identifies non-coding variants in the IL18RAP 3'UTR that reduce ALS risk by modulating neuro-inflammation through NF-κB signaling in microglia.
Laura Fumagalli, Florence L. Young, Steven Boeynaems…·Philip Van Damme
This study shows that C9orf72 repeat expansions produce toxic arginine-rich DPRs that disrupt axonal transport by interacting with microtubules and motor proteins, contributing to ALS/FTD.
Wouter van Rheenen, Sara L. Pulit, Annelot M. Dekker…·Jan Herman Veldink
Project MinE analyzes whole-genome sequencing data from ALS patients and controls to study genetic variation and its implications for disease susceptibility.