Pierre Sicard

This study identifies RyR2-dependent calcium leak as a mechanism underlying acute cardiovascular effects of ciguatoxin poisoning in human cardiomyocytes and rats.

This paper introduces a refined murine model of reversible aortic constriction to study cardiac functional recovery, finding that while function recovers, structural and fibrotic changes persist.

This study uses high-resolution echocardiography in mice to track hemodynamic force metrics during pressure overload and recovery, finding systolic HDF ratios strongly correlate with cardiac dysfunction and recovery.

This study examines age-related and sex-dependent cardiac dysfunction in Microcebus murinus by analyzing heart rate and variability under stress and autonomic modulation.

This paper introduces a high-resolution ultrasound-photoacoustic imaging method to monitor cerebral oxygenation dynamics in awake mice, showing changes under anesthesia and sensory stimulation.

This paper develops a mouse model of cardiac AL amyloidosis that reproduces human disease features, including amyloid deposits and cardiac dysfunction, and identifies a role for partial LC degradation in fibril formation.

This study shows that left atrial strain predicts cardiac dysfunction in a mouse model of pressure overload, with early detection before changes in volume or ejection fraction.

This study uses high-resolution ultrasound and speckle tracking to visualize and quantify fetal gastrointestinal motility in chick embryos, showing synchronized contractions develop late in fetal life.