Thomas Moore‐Morris

Simplified and refined murine model of reversible aortic constriction for characterizing cardiac functional recovery

This paper introduces a refined murine model of reversible aortic constriction to study cardiac functional recovery, finding that while function recovers, structural and fibrotic changes persist.

Ultrasound-Based Hemodynamic Force Trajectories in a Murine Model of Reversible Pressure Overload

This study uses high-resolution echocardiography in mice to track hemodynamic force metrics during pressure overload and recovery, finding systolic HDF ratios strongly correlate with cardiac dysfunction and recovery.

Left Atrial Strain as a Predictor of Cardiac Dysfunction in a Murine Model of Pressure Overload

This study shows that left atrial strain predicts cardiac dysfunction in a mouse model of pressure overload, with early detection before changes in volume or ejection fraction.

A human cell model of cardiac pathophysiological valvulogenesis

This paper develops a human pluripotent stem cell model to study valvulogenesis and disease, showing it can recapitulate valve development and disease traits like mitral valve prolapse.