Author

David John Ryan

Wellcome Sanger InstituteORCID 0000-0001-8906-2379Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Beiyuan FuiD· 2 shared Fengtang YangiD· 2 shared Pentao LiuiD· 2 shared A. W. Edith ChaniD· 1 shared Adam C. WilkinsoniD· 1 shared Aleksandra A. KolodziejczykiD· 1 shared Amaia Paredes‐RedondoiD· 1 shared Beatrice Lana· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Beiyuan FuORCID

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2 papers

Recent·Most cited

Molecular BiologyEMBO ReportsPeer-reviewedSep 30, 2019

Targeted gene correction of FKRP by CRISPR/Cas9 restores functional glycosylation of α-dystroglycan in cortical neurons derived from human induced pluripotent stem cells

Jihee Kim, Beatrice Lana, Silvia Torelli…·Yung‐Yao Lin

This paper corrects FKRP mutations in iPSCs using CRISPR/Cas9, restoring functional glycosylation of α-dystroglycan in cortical neurons and validating the role of FKRP in dystroglycanopathies.

22 citations

humanexperimental assay

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Developmental BiologybioRxivPreprintApr 6, 2017

Establishment In Culture Of Expanded Potential Stem Cells

Jian Ping Yang, David John Ryan, Wei Wang…·Pentao Liu

This paper establishes expanded potential stem cells (EPSCs) from mouse blastomeres and shows they can contribute to both embryo proper and trophoblasts in chimeras.

DOI 10.1101/124479

mousescRNA-seq

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