Aboozar Monavarfeshani

The paper reconstructs the evolutionary origins of retinal amacrine cell diversity using transcriptomic data from 24 vertebrate species, identifying 42 orthologous cell types and suggesting a hybrid precursor origin.

The paper compares retinal cell composition and visual coding between diurnal and nocturnal mice to show how evolutionary changes in cell types reconfigure visual information processing.

The paper integrates single-cell transcriptomic data from 17 vertebrate species to study the evolution of retinal cell types, finding conserved cell classes and subclasses with variation increasing from outer to inner retina.

This study identifies DNMT3a as a key inhibitor of optic nerve regeneration in adult mice and shows that its suppression restores vision after injury.

The paper creates a comprehensive human retina cell atlas using single-cell multi-omics data, revealing over 110 cell types and their gene regulatory networks, and enables fine-mapping of GWAS and eQTL variants.

The paper identifies four ATF/CEBP transcription factors that drive injury-induced neurodegeneration of retinal ganglion cells and shows their role in glaucoma.

The paper identifies LRRTM1 as a key molecule for retinothalamic convergence in the visual system and shows its role in visual behavior.