Wenjun Yan

The paper integrates single-cell transcriptomic data from 17 vertebrate species to study the evolution of retinal cell types, finding conserved cell classes and subclasses with variation increasing from outer to inner retina.

This study identifies DNMT3a as a key inhibitor of optic nerve regeneration in adult mice and shows that its suppression restores vision after injury.

The paper creates a comprehensive human retina cell atlas using single-cell multi-omics data, revealing over 110 cell types and their gene regulatory networks, and enables fine-mapping of GWAS and eQTL variants.

The paper identifies four ATF/CEBP transcription factors that drive injury-induced neurodegeneration of retinal ganglion cells and shows their role in glaucoma.

The paper identifies transcriptional programs that enhance survival and axon regeneration of injured retinal ganglion cells using single-cell transcriptomics and computational analysis.

The paper generates a chick retina cell atlas using scRNA-seq, identifying 136 cell types and analyzing their molecular and spatial organization.

The paper uses scRNA-seq to analyze 85,000 retinal cells from humans, identifies 58 cell types, and compares gene expression between fovea, peripheral retina, and macaques to study blinding diseases.

This paper identifies 63 amacrine cell types in the mouse retina using scRNA-seq and provides molecular markers, neurotransmitter profiles, and transcription factors for each type.

The paper identifies neuroprotective genes in retinal ganglion cells by analyzing their resilience to injury using single-cell RNA-seq and functional assays.

This study shows that the anterior piriform cortex actively maintains odor information during working memory delay periods in mice, even when performing a distracting task.

The paper classifies and compares cell types in primate fovea and peripheral retina using single-cell RNA-seq, finding conserved and divergent features across species and regions.