Christian Oertlin

This study identifies resistant subclones in pediatric lymphoma using scRNA-seq and scVDJ-seq, revealing progenitor-like cells and potential therapeutic targets like MSI2.

The paper introduces anota2seq, an algorithm for analyzing translational efficiency from ribosome or polysome profiling data, revealing translational buffering and mTOR-dependent gene regulation.

This paper presents an optimized non-linear sucrose gradient method for polysome-profiling that reduces sample handling and enables translatome analysis from small tissue samples and primary cells.