Author

Angélique Buton

University of Massachusetts Chan Medical SchoolORCID 0000-0001-8937-5535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Stéphanie PuigiD· 2 shared Anita KhasnavisiD· 1 shared Ari Benjamin Ginsparg· 1 shared Ashley K. McDonald· 1 shared Gilles MartiniD· 1 shared Ishaan U. PateliD· 1 shared Jaqueline A. Martinez· 1 shared Kathryn M. AlbersiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

Stéphanie PuigORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pharmacology & Toxicologynpj Drug Discovery.Peer-reviewedJul 21, 2026

Prioritizing Neuroactive Ligands Using Motif-Guided Virtual Discovery and Zebrafish Profiling

Ari Benjamin Ginsparg, Jaqueline A. Martinez, Ishaan U. Patel…·Summer B. Thyme

The paper develops a computational method to prioritize neuroactive ligands using structural data and zebrafish testing, identifying effective antagonists for hypocretin receptors.

DOI 10.1038/s44386-026-00058-1

zebrafishproteomics

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NeurosciencebioRxivPreprintMay 14, 2024

Peripheral opioid tolerance involves skin keratinocytes and platelet-derived growth factor type B signaling

Luca Posa, Sophia A. Miracle, Kathryn M. Albers…·Stéphanie Puig

This study identifies keratinocytes and PDGF-B/PDGFRβ signaling as key mediators of peripheral opioid tolerance in mice, showing that PDGF-B release from keratinocytes drives tolerance through activation of PDGFRβ in sensory neurons.

DOI 10.1101/2024.05.14.594040

mouseexperimental assay

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