Author

Deirdre M. Logsdon

Colorado Center for Reproductive Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

William B. SchoolcraftiD· 2 shared Ye YuaniD· 2 shared Ana Elisa Ribeiro OrsiiD· 1 shared Asrafun Nahar· 1 shared Bilge BirsoyiD· 1 shared Bo Thorstenson· 1 shared Brian F. NiemeyeriD· 1 shared Caitlen Stobbe· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

William B. SchoolcraftORCID

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3 papers

Recent·Most cited

Attenuated estrogen signaling disrupts placentation and drives trophoblast defects in Down syndrome

Deirdre M. Logsdon, Isabela Tiemy Pereira, Kindyll Wetta, Lauren S. Ohler, Mika Nevo, Bo Thorstenson, Brian F. Niemeyer, Bilge Birsoy, Lynae Smith, Cameron Hebert, John L. Rinn, Matthew D. Galbraith, Mary Ann Allen, Robin D. Dowell, Joaquin Maximiliano Espinosa, , Justin Brumbaugh

This study identifies attenuated estrogen signaling and NRIP1 as key factors in trophoblast defects in Down syndrome using patient-derived stem cells.

bioRxiv · Jun 8, 2026 · PreprintDevelopmental Biology

In Vitro Culture Alters Cell Lineage Composition and Cellular Metabolism of Bovine Blastocyst

Hao Ming, Mingxiang Zhang, Sandeep K. Rajput, Deirdre M. Logsdon, Linkai Zhu, William B. Schoolcraft, Rebecca Lynn Krisher, Zongliang Jiang, Ye Yuan

The paper uses single-cell transcriptomics to compare bovine blastocysts cultured in vivo versus in vitro under different conditions, revealing how culture affects cell lineage and metabolism.

Biology of Reproduction · Feb 26, 2024Peer-reviewedDevelopmental Biology

Large scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal crosstalk

Leqian Yu, Deirdre M. Logsdon, Carlos A. Pinzón-Arteaga, Jialei Duan, Toshihiko Ezashi, Yulei Wei, Ana Elisa Ribeiro Orsi, Seiya Oura, Lizhong Liu, Lei Wang, Kun Liu, Xiaoyun Ding, Linfeng Zhan, Junfei Zhang, Asrafun Nahar, , Jun Wu

This paper develops an optimized protocol for large-scale production of human blastoids and identifies signaling pathways and endometrial stromal effects in blastocyst development.

Cell stem cell · Sep 1, 2023Peer-reviewedDevelopmental Biology