Laura Anne Lowery

This study investigates the role of 16p12.1 deletion orthologs in craniofacial development by analyzing their expression and function in Xenopus laevis neural crest cells.

The paper tests a 'two-hit' model for neurodevelopmental defects by examining interactions between 16p12.1 homologs and 'second-hit' genes in Drosophila and Xenopus laevis, finding genetic interactions in 63% of tested pairs.

This study identifies NCBP2 as a key modifier gene in the 3q29 deletion, showing it enhances developmental defects through disrupted apoptosis and cell cycle mechanisms in Drosophila and Xenopus models.

The paper investigates the role of WHS-associated genes in craniofacial development by analyzing their expression and functional impact in Xenopus laevis.