Author

Francesca Launchbury

UCL Queen Square Institute of NeurologyORCID 0000-0001-9029-2147Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison VanSchoiackiD· 1 shared Aya Balbaa· 1 shared Damian M. CummingsiD· 1 shared Eugenia WongiD· 1 shared Frances A. EdwardsiD· 1 shared Jack I. WoodiD· 1 shared John HardyiD· 1 shared Jörg HanriederiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alison VanSchoiackORCID

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1 paper

Recent·Most cited

Upregulation of Trem2 expression occurs exclusively on microglial contact with plaques

Jack I. Wood, Eugenia Wong, Ridwaan Joghee, Aya Balbaa, Karina S. Vitanova, Alison VanSchoiack, Stefan-Laural J. Phelan, Francesca Launchbury, Sneha Desai, Takshashila Tripathi, Jörg Hanrieder, Damian M. Cummings, John Hardy, Frances A. Edwards

The paper shows that Trem2 gene expression in microglia is upregulated only when they contact plaques, and this effect is reduced by the Trem2R47H mutation.

bioRxiv · Jan 26, 2022 · PreprintNeuroscience