Christian Dide-Agossou

This study evaluates the CFU-16S rRNA gap in tuberculosis treatment models, finding that the discrepancy is partially due to residual 16S rRNA from dead bacteria and potential transient viable but non-culturable populations.

The paper uses SEARCH-TB to analyze drug interactions in M. tuberculosis by measuring transcriptional responses to the BPaL regimen in vivo, showing complex effects of drug combinations.

This study examines how prolonged antibiotic treatment affects M. tuberculosis physiology in mice, finding that sterilizing and non-sterilizing antibiotics induce distinct transcriptional responses.