Author

María Jesús Larriba

Consejo Superior de Investigaciones CientíficasORCID 0000-0001-9035-7414Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Alberto MúñoziD· 2 shared Alfonso Herreros‐CabelloiD· 1 shared Ana Chocarro‐CalvoiD· 1 shared Antonio BarbáchanoiD· 1 shared Asunción Fernández‐BarraliD· 1 shared Aurora BurgosiD· 1 shared Custodia García‐JiméneziD· 1 shared Damián García‐OlmoiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Alberto MúñozORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 17, 2025

Age-dependent chemotherapy response and vitamin D impact in paired patient-derived normal and tumor colorectal organoids

Asunción Fernández‐Barral, Antonio Barbáchano, Silvia Rodriguez-Marrero…·Alberto Múñoz

The paper shows age-dependent differences in chemotherapy response and vitamin D's effect on drug sensitivity in colorectal organoids from early-onset and late-onset CRC patients.

DOI 10.64898/2025.12.15.694334

humanorganoid / primary culture

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Cancer BiologyInternational Journal of Biological SciencesPeer-reviewedJan 1, 2024

SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells.

José Manuel García-Martínez, Ana Chocarro‐Calvo, Javier Martínez‐Useros…·Custodia García‐Jiménez

This study shows that vitamin D inhibits the Wnt/β-catenin pathway in colon cancer cells by activating SIRT1, which deacetylates and excludes β-catenin from the nucleus, reducing tumor growth.

16 citations

humanexperimental assay

𝕏 PostBluesky