Author

Annabelle Klein

Centre National de la Recherche ScientifiqueORCID 0000-0001-9058-844XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Muriel RhinniD· 3 shared William M. KeyesiD· 3 shared Daniel Sampaio GonçalvesiD· 2 shared Ludivine DulaciD· 2 shared Tania Knauer-Meyer· 2 shared A. MeunieriD· 1 shared Adelyne Sue Li ChaniD· 1 shared Bernard JostiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Muriel RhinnORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 30, 2025

Senescent cells exhibit features of developmental signaling centres

Daniel Sampaio Gonçalves, Ludivine Dulac, Birgit Ritschka…·William M. Keyes

This study identifies senescent cells as resembling developmental signaling centers by showing their SASP activates conserved developmental pathways across species.

2 citations

humanmouse

𝕏 PostBluesky

Cell BiologybioRxivPreprintOct 30, 2025

Developmental senescence profiling reveals Eda2r as a common mediator in the core senescence program

Annabelle Klein, Daniel Sampaio Gonçalves, Ludivine Dulac…·William M. Keyes

The paper identifies Eda2r as a key mediator in both developmental and pathological senescence by profiling senescent cells in mouse limb development and comparing them to in vitro and in vivo models.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyPLoS BiologyPeer-reviewedJun 14, 2022

Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects

Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein…·William M. Keyes

The paper investigates how aberrant p19Arf-mediated cellular senescence in neuroepithelial cells contributes to VPA-induced developmental defects in embryos.

33 citationstop 2%

mouseexperimental assay

𝕏 PostBluesky

GenomicsMolecular MetabolismPeer-reviewedAug 2, 2021

Extensive NEUROG3 occupancy in the human pancreatic endocrine gene regulatory network

Valérie Schreiber, Reuben Mercier, Sara Jiménez…·Gérard Gradwohl

This study maps NEUROG3 occupancy in human pancreatic endocrine progenitors, identifying 1268 target genes and linking NEUROG3 to islet cell development and type 2 diabetes risk variants.

39 citationstop 3%

humanChIP-seq

𝕏 PostBluesky