Katarzyna M. Tych

The paper identifies a shared topological organisation in divergent arenavirus intergenic RNAs using graph theory and structural analysis.

This study uses single-molecule force spectroscopy and molecular dynamics to analyze the unfolding and folding of double-knotted and single-knotted proteins, revealing that double-knotted proteins require chaperone assistance for full knotting.

This paper develops a one-pot dual protein labelling method using orthogonal reactions to enable simultaneous mechanical and fluorescent readouts in optical tweezers for studying protein conformational dynamics.

This paper demonstrates hybrid polymer-lipid membranes that enable stable nanopore sensing in human serum, showing native-like nanopore behavior and efficient analyte sampling.

The paper investigates how ligand-induced oligomer dissociation affects enzyme diffusion using mass photometry, finding substrate-induced dissociation in some enzymes and not others.

This study investigates protein translocation through nanopores, finding that blob-like structures form during transport, and identifies conditions for single-file transport.