Author

Laura‐Marie Silbermann

University of GroningenORCID 0000-0001-5989-1774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:fluorescence / live-cell microscopy· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Katarzyna M. TychiD· 2 shared Fernando Bruno da SilvaiD· 1 shared Iwona LewandowskaiD· 1 shared Joanna Ida SulkowskaiD· 1 shared Kathrin LangiD· 1 shared Maciej SikoraiD· 1 shared Mateusz Fortunka· 1 shared Maximilian FottneriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

Katarzyna M. TychORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 27, 2025

Multi-barrier unfolding of the double-knotted protein, TrmD-Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

Fernando Bruno da Silva, Szymon Niewieczerzał, Iwona Lewandowska…·Joanna Ida Sulkowska

This study uses single-molecule force spectroscopy and molecular dynamics to analyze the unfolding and folding of double-knotted and single-knotted proteins, revealing that double-knotted proteins require chaperone assistance for full knotting.

DOI 10.1101/2025.08.27.672562

mechanistic / dynamical modelexperimental assay

𝕏 PostBluesky

BiophysicsProtein SciencePeer-reviewedMar 18, 2025

One-Pot Dual Protein Labelling for Simultaneous Mechanical and Fluorescent Readouts in Optical Tweezers

Laura‐Marie Silbermann, Maximilian Fottner, Ronald van der Meulen…·Katarzyna M. Tych

This paper develops a one-pot dual protein labelling method using orthogonal reactions to enable simultaneous mechanical and fluorescent readouts in optical tweezers for studying protein conformational dynamics.

3 citations

fluorescence / live-cell microscopyexperimental assay

𝕏 PostBluesky