Alexander Belyy

This paper introduces a direct enzymatic bioconjugation platform using the flavin transferase ApbE, enabling site-specific conjugation of diverse payloads without intermediate chemical steps.

This study shows that actin and AnkJ reciprocally regulate the catalytic activity of Ceg14 by remodeling its catalytic center.

The paper presents the cryo-EM structure of Ptx2, a VasX family effector, revealing its multi-domain architecture and conformational flexibility, and identifies key features for its toxic activity.

The paper determines the structure of the F-tractin-F-actin complex using cryo-EM, revealing how F-tractin binds actin and induces bundling.

The paper investigates how ligand-induced oligomer dissociation affects enzyme diffusion using mass photometry, finding substrate-induced dissociation in some enzymes and not others.

This study investigates the multi-state kinetics of Tc toxin prepore-to-pore transition, identifying intermediate states and transition times under various conditions.

This paper determines the structure of the Lifeact-F-actin complex and shows how Lifeact competes with other actin-binding proteins, affecting cell morphology.