Author

Iwona Lewandowska

University of WarsawORCID 0000-0003-4354-4350Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Fernando Bruno da SilvaiD· 1 shared Joanna Ida SulkowskaiD· 1 shared Katarzyna M. TychiD· 1 shared Laura‐Marie SilbermanniD· 1 shared Maciej SikoraiD· 1 shared Mateusz Fortunka· 1 shared Szymon NiewieczerzałiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Fernando Bruno da SilvaORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 27, 2025

Multi-barrier unfolding of the double-knotted protein, TrmD-Tm1570, revealed by single-molecule force spectroscopy and molecular dynamics

Fernando Bruno da Silva, Szymon Niewieczerzał, Iwona Lewandowska…·Joanna Ida Sulkowska

This study uses single-molecule force spectroscopy and molecular dynamics to analyze the unfolding and folding of double-knotted and single-knotted proteins, revealing that double-knotted proteins require chaperone assistance for full knotting.

DOI 10.1101/2025.08.27.672562

mechanistic / dynamical modelexperimental assay

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