Author
Huntsman Cancer InstituteORCID 0000-0001-9092-0529Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Mélanie A. Dacheux, Mengting Wu, Michael T. Scherzer…·Aria Vaishnavi
This study shows that BRAFV600E-driven lung cancer requires ERBB receptor signaling via ligand-mediated activation, and combined inhibition of BRAFV600E and ERBB improves therapeutic outcomes.
Yiqin Ma, Stephen M. Pronovost, Mitchell R. Lewis…·Bruce A. Edgar
The paper shows that growth factor signaling promotes cell proliferation by inducing tRNAs that decode rare codons, enhancing translation of DNA replication factors.
Tanya Chhibber, Michael T. Scherzer, Anastasia Prokofyeva…·Paris Jafari
This study develops UCL-211, a transdermal delivery system for miR211-5p, which stabilizes BRAFV600E+ melanocytic nevi by maintaining them in a growth-arrested state.
Phaedra C. Ghazi, Kayla T. O’Toole, Sanjana Srinivas Boggaram…·Martin McMahon
This study shows that combining ULK1/2 inhibition with KRASG12C inhibitors reduces lung cancer growth in preclinical models.