Author
University of UtahORCID 0000-0001-5614-8627Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Mona Foth, Wontak Kim, Kayla T. O’Toole…·Martin McMahon
This study identifies RAS(ON) inhibitors effective against NRAS-mutated melanoma and reveals resistance mechanisms through Ppia and Map2k1 mutations.
Mélanie A. Dacheux, Mengting Wu, Michael T. Scherzer…·Aria Vaishnavi
This study shows that BRAFV600E-driven lung cancer requires ERBB receptor signaling via ligand-mediated activation, and combined inhibition of BRAFV600E and ERBB improves therapeutic outcomes.
Phaedra C. Ghazi, Kayla T. O’Toole, Sanjana Srinivas Boggaram…·Martin McMahon
This study shows that combining ULK1/2 inhibition with KRASG12C inhibitors reduces lung cancer growth in preclinical models.